Multiple sclerosis after immunization with the Pfizer-BioNTech COVID-19 vaccine

manifestation of #MultipleSclerosis after immunization with the Pfizer-BioNTech COVID-19 vaccine:

First manifestation of multiple sclerosis after immunization with the Pfizer-BioNTech COVID-19 vaccine

• Joachim Havla, 
• Yannick Schultz, 
• Hanna Zimmermann, 
• Reinhard Hohlfeld, 
• Adrian Danek & 
• Tania Kümpfel 

A 28-year-old woman developed the first clinical manifestation of relapsing MS after vaccination with the Pfizer-BioNTech COVID-19 vaccine (BNT162b2, Comirnaty©, BioNTech/Pfizer). Six days after the initially well-tolerated first immunization, she began to develop left abdominal neuropathic pain, sensory impairment below the T6 level, with hypoesthesia of right abdominal wall and genital regions, and left leg paresis. Magnetic resonance imaging (MRI) of the spinal cord on day 18 after vaccination showed a contrast-enhancing lesion at the T6 level, suggestive of myelitis, and cerebral MRI revealed multiple (> 20), partially confluent lesions with spatial dissemination but no Gadolinium enhancement.

We are not aware of any published cases of initial MS manifestation after vaccination with Pfizer-BioNTech COVID-19 vaccine.

CONTINUE HERE https://link.springer.com/article/10.1007/s00415-021-10648-w