Death: 5 days after the first dose of the #Covidvaccine (Pfizer–BioNTech): chest pain, then became unconscious

 22-year-old man

- 5 days after the first dose of the #Covidvaccine (Pfizer–BioNTech): chest pain, then became unconscious ⇒ Atrial myocarditis "Cardiopulmonary resuscitation was performed for two hours, but he could not be resuscitated"

Myocarditis-induced Sudden Death after BNT162b2 mRNA COVID-19 Vaccination in Korea: Case Report Focusing on Histopathological Findings
Sangjoon Choi,1 SangHan Lee,1 Jeong-Wook Seo,2 Min-ju Kim,2 Yo Han Jeon,1 Ji Hyun Park,1 Jong Kyu Lee,1 and Nam Seok Yeo1
1Department of Forensic Medicine, Defense Institute of Forensic Science, Criminal Investigation Command, Ministry of National Defense, Seoul, Korea.
2Department of Pathology, Incheon Sejong Hospital, Incheon, Korea.

Address for Correspondence: SangHan Lee, MD. Department of Forensic Medicine, Defense Institute of Forensic Science, Criminal Investigation Command, Ministry of National Defense, 22 Itaewon-ro, Yongsan-gu, Seoul 04383, Korea. Email: sanghan111@gmail.com
Received August 24, 2021; Accepted October 01, 2021.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.


Abstract

We present autopsy findings of a 22-year-old man who developed chest pain 5 days after the first dose of the BNT162b2 mRNA vaccine and died 7 hours later. Histological examination of the heart revealed isolated atrial myocarditis, with neutrophil and histiocyte predominance. Immunohistochemical C4d staining revealed scattered single-cell necrosis of myocytes which was not accompanied by inflammatory infiltrates. Extensive contraction band necrosis was observed in the atria and ventricles. There was no evidence of microthrombosis or infection in the heart and other organs. The primary cause of death was determined to be myocarditis, causally-associated with the BNT162b2 vaccine.


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https://jkms.org/DOIx.php?id=10.3346/jkms.2021.36.e286


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